Cardiovascular and Metabolic Trials Experience
More than any other therapeutic area, cardiovascular and metabolic compounds typically require large international Phase IIb/III trials to achieve results with statistical significance. Sponsors face significant obstacles in recruiting patients for such large trials, as well as designing trials that produce the right endpoints while protecting patient safety.
PAREXEL helps you meet those challenges with well-planned, efficiently managed, and on-time pivotal clinical trials for cardiovascular and metabolic disorders around the world. We have monitoring experience in more than 60 countries and a global database of 9,000 cardiovascular and metabolic investigators. We have conducted hundreds of studies in these therapeutic areas, including studies with as many as 4,500 sites. PAREXEL also maintains relationships with leading academic research centers – often working with them to manage large-scale trials.
PAREXEL offers in-depth clinical expertise that helps keep your pivotal trials on track. Our staff includes more than 100 physicians with specific cardiovascular and metabolism experience, and our project managers have been working in clinical research for an average of 11 years. This broad range of experience means that we have probably managed a Phase III trial in whatever cardiovascular or metabolic area your product is targeting. In the past five years, we have conducted nearly 400 trials for indications such as acute coronary syndromes, coronary artery disease, PAD/thrombosis, pulmonary hypertension, venous diseases, arrhythmia, diabetes, arterial hypertension, obesity, heart failure, and many others.
Our therapeutic expertise is supported by world-class medical imaging technology and personnel that can assess and adjudicate clinical endpoints and ensure that your image acquisition meets the highest clinical and medical standards. In addition, PAREXEL leads the industry in eClinical technologies that allow cardiovascular and metabolism specialists from around the world to participate in blind adjudication panels via the internet – sharing images, consulting with colleagues, and rendering decisions. Known at the “Virtual Panel System” for endpoint management, this system provides automatic tracing of each event and related images and documents.