Developing innovative cardiovascular and metabolic therapies

Cardiovascular diseases claim millions of lives around the world each year.  Diabetes and other metabolic disorders are also widespread, affecting millions of people in the US alone.  Although the demand for novel therapies is large, sponsors face significant obstacles in developing new treatments for these diseases, including recruiting patients for large pivotal trials, and designing trials that produce solid endpoints and protect patient safety. 

PAREXEL helps you meet those challenges with well-planned, efficiently managed, and on-time clinical trials for cardiovascular and metabolic disorders around the world.  Our experienced medical experts provide best-practices management across these therapeutic areas, including drug development, Phase I-IV trials, regulatory consulting, and post-marketing studies. 

Cardiovascular and metabolic studies often require extremely large international studies to produce statistically valid results.  With monitoring experience in more than 60 countries and a database of 9,000 investigators worldwide, PAREXEL can keep even your largest studies moving forward quickly and efficiently.  In the last few years, we have conducted hundreds of studies in these therapeutic areas, including studies with 2,000+ sites on multiple continents.  We also have dedicated early-phase facilities in the US, Europe, and South Africa with 600 in-patient beds to handle your complete clinical pharmacology and Phase I trial requirements.

PAREXEL’s trial experience in cardiology includes numerous trials studying acute coronary syndromes, thrombosis, pulmonary hypertension, arrhythmia, diabetes, obesity, heart failure, and many others.  This experience, plus our understanding of the underlying mechanisms of these diseases, helps our cardiologists and endocrinologists provide valuable advice about study design, patient and site selection, and regulatory issues.  Our therapeutic expertise is supported by world-class medical imaging technology and personnel that can assess and adjudicate clinical endpoints and ensure that your image acquisition meets the highest clinical and medical standards.

Whether your company is large or small, you can rely on PAREXEL for cardiovascular and metabolic expertise that improves your chances for clinical success and gets your products to patients who need them around the world.