The future of clinical trials has never been in more need of innovation to keep advancing against

patient needs. Advances in technology, scientific discovery, data processing, and ways of engaging

patients are moving clinical research to the bleeding edge. And with R&D investments by

sponsors continuing to escalate, with one estimate putting expenditures at $233 billion in 2026

up from $186 billion in 2019, innovative thinking by leaders spanning the drug development

journey are needed to bring new breakthrough medicines to market to meet a multitude of

unmet therapeutic need.

Within this eBook, Parexel subject matter experts speak to some of the exciting trends that

are moving the industry toward the drug development of the future, including the next era

of precision medicine based on identifying tumor agnostic therapies, linking real world data

to connect the dots for improved therapeutic outcomes, using synthetic control arms to link

patients across multiple datasets using RWE, engaging patients in new ways to participate in

virtual or decentralized trials, and addressing the very specific needs of patients and caregivers

in the realm of rare diseases. The common theme throughout this publication is a dedication to

innovation and moving the needle of drug development and clinical trials forward and a future

where patients are at the heart of the process.