View 4 related solutions for
Adaptive clinical trials can offer enormous potential in today's drug development process. They can facilitate better decision making by enabling more dose levels to be studied in Phase II dose-finding studies whilst maintaining practical sample sizes. They can also reduce the time between development phases using seamless designs and aid in the early identification of failing compounds.
Rapid access to patient safety and efficacy data, from which decisions can be made, is critical to adaptive clinical trials' ability to make mid-study changes. Furthermore, it is essential to be able to quickly and simply implement changes to the randomization algorithm and respond immediately to the resulting changes in medication supply requirements, ideally without detection by trial personnel.
PAREXEL Informatics is one of the leading providers of key technology components to support adaptive trials, integrating EDC, ePRO, IVR, supplies simulation and forecasting. PAREXEL provides expert consulting on supplies planning and optimal technology implementation for adaptive trials. Combined with this consulting expertise, our integrated suite of leading technology solutions provides the necessary building blocks required to implement an adaptive trial design.
• Technology implementation consulting
• Trial supply planning
• Fully integrated technology solution for clinical data collection, randomization, and trial supply management
• Single project manager coordinating all technology delivery
• Full hosting and integration with Bayesian response adaptive algorithms
Electronic Data Capture
The DataLabs® EDC (Electronic Data Capture) solution is uniquely focused on simplifying workflows and delivering superior user experiences. Its advanced EDC features help streamline the entire process starting from study design all the way to collection, management and reporting of clinical trial data.
Randomization and Trial Supply Management
PAREXEL® Informatics provides automated randomization and supplies management through its ClinPhone® RTSM (Randomization and Trial Supply Management) solution. Our services are offered by the industry's most experience and trusted provider of IVR (Interactive Voice Response) and IWR (Interactive Web Response) technologies.
Electronic Clinical Outcome Assessments (eCOA)
Clinical Outcome Assessments (COAs) measure a patient’s symptoms, overall mental state, or the effects of a disease or condition on how the patient functions. COAs can be used to determine whether or not a drug has been demonstrated to provide treatment benefit. COA types include ePRO (electronic Patient Reported Outcomes).