Gastroenterology Imaging Expertise

Gastroenterology Imaging Expertise

As a leading central review core lab for clinical trials, we offer several solutions to standardize central endpoint assessments in gastrointestinal diseases (GI).  Parexel has a dedicated GI imaging unit, which is led by a team of GI imaging experts and Operations leads. With Parexel you are supported by in-house medical imaging and medical writing expertise complemented by specialized key opinion leaders and scientific advisors.

In addition to standard endoscopies (colonoscopies, flexible sigmoidoscopies, and upper GI endoscopies) the use of cross-sectional imaging techniques for suspected small bowel disorders has increased over the past several years. Cross-sectional imaging, such as CT and MRI, allow visualization of the entire bowel, without overlapping bowel loops, and detection of extraluminal pathologic conditions. Improvements in MRI hardware and software have enabled MRI to assume a major role in the evaluation of the small and large bowel. MRI has several advantages, such as a lack of ionizing radiation (good for repeat imaging) and excellent soft tissue contrast. Parexel has more than a dozen fulltime MR experts (technologists, PhDs, MDs, and radiologists).

For a recent colonoscopy trial where central reviewers needed to be mobile, Parexel Integrated Technologies developed a unique workflow to allow reviewers to conduct their reads on iPads, in any location with internet access.  Using this approach, Parexel converted colonoscopy videos to an iPad native format as part of the image quality control process. The reviewer logged into a 21 CFR Part 11 compliant electronic analysis application deployed on our website to perform the review. Digital analysis data was immediately transmitted back to Parexel at time of electronic CRF sign off.  

  • Modalities
    • CT
    • MRI
    • Colonoscopy
    • Flexible sigmoidoscopies
    • Upper GI endoscopies
    • Abdominal ultrasound
    • Barium exam of the bowel
    • PET
  • Indications
    • Crohn’s disease
    • Ulcerative colitis
    • GI malignancies including Colorectal cancer
    • Gallstones
    • Iron / fat content of the liver
    • Liver volume
    • Liver scarring / cirrhosis
    • Pouchitis

 

Scientific Advisor: Paul Rutgeerts

We are always available for a conversation.

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