Ophthalmology Imaging Expertise

Opthalmology Imaging Expertise

The Parexel Informatics medical imaging team supports pharmaceutical clients in the investigation of new therapies for various ophthalmic diseases by leveraging its proven global clinical trial support and partnerships with key academic leaders. Parexel has experience executing large phase II/III trials whereby ophthalmic imaging assessments are being used to support both safety and efficacy outcomes.

Advantages to partnering with us:

  • Global foot print: A global presence and  24/7 site support with Parexel Medical Imaging offices, located in the following countries: Massachusetts; USA, Berlin; Germany, Hyderabad; India, and Kobe; Japan.
  • Experience: Supporting many large phase III trials that have received regulatory approval. Several active protocols supporting safety and efficacy reads within ophthalmology; i.e., ophthalmic assessments as safety endpoints for trials in neurological disorders, diabetic macular edema and Hepatitis C complications.
  • Communication: Continuous data quality monitoring and active feedback. Full-time operational, technological, and medical staff. Strong Project Management staff to monitor timelines, budget, scope and any potential risks.
  • Network & Expertise: Combined global expertise from Parexel (operations, technology, and regulatory rigor) and independent readers/reading centers (medical expertise, consultation on criteria, analysis of the images) to provide support for your clinical trial. We have access to over 100 ophthalmologists and ocular disease experts.
  • Technology: FDA approved and 21 CFR part 11 compliant technology that allows easy access to raw and analyzed images. 

Indications:

  • Age-related macular degeneration (wet and dry)
  • Cataract
  • Diabetic macular edema
  • Diabetic retinopathy
  • Geographic Atrophy
  • Glaucoma
  • Neuro-Ophthalmology
  • Ocular complications of AIDS
  • Ocular Oncology
  • Optic Neuritis
  • Retinal vascular occlusive disease
  • Uveitis

Imaging Modalities:

  • Spectral Domain Optical coherence tomography (SD-OCT)
  • Color fundus photography (CFP)
  • Fundus autofluorescence (FAF); Confocal Scanning Laser Ophthalmoscopy (cSLO)
  • Fluorescein angiography (FA); Indocyanine Green Angiography (ICG)
  • Ultra-wide field angiography, Photography
  • Slit lamp/Iris Photography
  • Specular microscopy for endothelial cell counts

Non-imaging modalities:

  • Humphrey visual field
  • Microperimetry for dark adaptation
  • Electroretinograph
  • Electrooculography

We are always available for a conversation.

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