Floris Höppener, M.D.


Floris Höppener, M.D.

Global TA Section Head, Phase 1 & Rare Tumors

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Floris is a physician with more than 25 years of experience in clinical drug development and is the Global Therapeutic Area Section Head for Phase 1 and Rare Tumors/Senior Medical Director based in Amsterdam for the Oncology department within Parexel Global Medical Services. In this role, he provides leadership to the group of physicians involved in early phase oncology studies and studies involving rare cancer indications. He also provides Medical Monitoring support for assigned early phase oncology studies.

Work experience

Floris has over 25 years of experience in Early Phase Drug Research obtained both in the CRO environment and within the pharmaceutical industry. This research experience includes more than 10 years of involvement in early phase oncology projects including projects involving radiopharmaceuticals. He has acted as principal investigator for Phase 1 studies for over 12 years. This experience included working on many types of clinical pharmacology studies, including food effect, DDI, TQT and ADME studies. Floris has experience in the following therapeutic areas: Oncology, respiratory, immunology, rheumatology, neurology including pain research, infectious diseases and obstetrics/gynecology.


Floris was educated in General Medicine at the University of Nijmegen in The Netherlands and received training in Clinical Pharmacology at Utrecht University. He gained practical clinical experience in the fields of surgery and obstetrics & gynecology. His special research interest includes first in-patient studies, Early Phase oncology studies and Clinical Pharmacology studies. He is a member of the Dutch Society for Clinical Pharmacology and The American Society for Clinical Oncology and has been involved in teaching Pharmacotherapy in the Utrecht medical school. Floris is first author or co-author of over 20 scientific publications.