Capital, Conviction, and the Reality of Building an Innovative Biotech
In this episode of Clinical Trialblazers, host Alberto Grignolo sits down with Paul Garofolo, Co-Founder and CEO of Locus Biosciences. Paul reflects on his journey from Chief Technology Officer at Patheon to founding a next-generation bacteriophage-based precision medicine company and shares valuable insights into building and leading through market cycles, funding challenges, and scientific uncertainty. This conversation offers practical wisdom for anyone building or leading in biotech – from prioritizing the right programs to understanding what data truly matters for regulatory success.
Related Insights
CTB Blog
Decoding FDA's new ‘plausible mechanism framework’ guidance: what drug developers need to know
Feb 27, 2026
CTB Report
Faster paths to proof of concept
Feb 19, 2026
CTB Podcast
Leadership Lessons from Biotech Innovators
Nov 18, 2025
CTB Podcast
Building Biotech Success: Insights from Venture Capitalist Dr. Geeta Vemuri
Nov 18, 2025
CTB Podcast
Breaking Barriers in Gene Therapy: Miquel Vila-Perello's Vision for Curing Untreatable Diseases
Sep 15, 2025
CTB Podcast
Investing in Innovation: Lyla Bibi’s Perspective on Biotech Markets
Aug 11, 2025
CTB Podcast
The Finnish Formula: Finding Balance and Building Innovation with Dr. Antti Vuolanto
Jul 14, 2025
CTB Podcast
Leading with Science and Heart: Building a Resilient Biotech
Jun 9, 2025
CTB Podcast
Bedside to Biotech: Building Trust, Storytelling in Science, and Pediatric Cancer Innovation
May 12, 2025
CTB Podcast
From Mentee to CEO, Board Member and Mentor
Apr 17, 2025
CTB Podcast
Leading through setbacks with Cytokinetics
Mar 26, 2025
CTB Podcast
Pioneering oncology trials with AVEO Oncology
Mar 11, 2025
Related Insights
CTB Blog
Decoding FDA's new ‘plausible mechanism framework’ guidance: what drug developers need to know
Feb 27, 2026
CTB Report
Faster paths to proof of concept
Feb 19, 2026
CTB Podcast
Leadership Lessons from Biotech Innovators
Nov 18, 2025
CTB Podcast
Building Biotech Success: Insights from Venture Capitalist Dr. Geeta Vemuri
Nov 18, 2025
CTB Podcast
Breaking Barriers in Gene Therapy: Miquel Vila-Perello's Vision for Curing Untreatable Diseases
Sep 15, 2025
CTB Podcast
Investing in Innovation: Lyla Bibi’s Perspective on Biotech Markets
Aug 11, 2025
CTB Podcast
The Finnish Formula: Finding Balance and Building Innovation with Dr. Antti Vuolanto
Jul 14, 2025
CTB Podcast
Leading with Science and Heart: Building a Resilient Biotech
Jun 9, 2025
CTB Podcast
Bedside to Biotech: Building Trust, Storytelling in Science, and Pediatric Cancer Innovation
May 12, 2025
CTB Podcast
From Mentee to CEO, Board Member and Mentor
Apr 17, 2025
CTB Podcast
Leading through setbacks with Cytokinetics
Mar 26, 2025
CTB Podcast
Pioneering oncology trials with AVEO Oncology
Mar 11, 2025