BIO
Jackie Vanderpuye-Orgle, Ph.D.
Senior Vice President, and Global Head of Advanced Analytics, RWE & HEOR
Explore end-to-end solutions throughout development — from portfolio optimization and regulatory strategy, to Phase I-IV clinical trials, market access planning, and more.
Our team optimizes your portfolio utilizing integrated expert clinical, regulatory, and market access strategies, enabling earlier and more informed risk-reward decisions.
Our multi-disciplinary early phase approach accelerates the path to proof of concept by integrating diverse expertise to optimize study design, generate robust clinical evidence, and reduce gaps between development phases.
We deliver whole-study solutions with integrated strategies that ensure safety, data integrity, and regulatory compliance. We design patient-informed protocols that remove participation barriers, accelerate enrollment, and increase the likelihood of successful drug launches.
Our team of former regulators and HTA professionals provide tailored regulatory, compliance, and market access strategies across specialized therapeutic areas, creating customized pathways to maximize global market reach throughout your product's lifecycle.
We enhance your product's value story through post-approval studies and holistic lifecycle management services that satisfy regulators and payers while building stakeholder trust and maximizing your drug's market impact throughout its entire lifecycle.
ParexelAI leverages our full suite of AI capabilities to deliver with greater speed, quality, and efficiency.

ParexelAI
ParexelAI is a proprietary AI-enabled clinical development suite that accelerates patient outcomes by combining Parexel's operational expertise with cutting-edge AI technology.
Utilize our expertise across therapeutic areas, combining innovative trial designs, leading clinical and regulatory expertise, global reach, and a passion for changing patient lives.
Our team delivers high-quality clinical trials through forward-thinking medical expertise across multiple indications by combining strategic insight with operational excellence to support programs of all sizes.
Our infectious disease and vaccines cro services help treat and prevent life-threatening illnesses. Learn how our team of experts can aid in any complex trial.
Discover our inflammation and immunology CRO services. We bring agile support and a unique MOA-driven model to inflammation and immunology.
Parexel is a leading Oncology CRO with more than 80 ex-agency regulators and nearly 2,500 sites globally. Learn more about our oncology indications.
As a leading neuroscience CRO, we leverage global site relationships, specialized resources, and indication-specific expertise to accelerate breakthroughs in neurological and psychiatric treatments for patients worldwide.
As a top hematology CRO, our integrated teams use advanced analytics and real-world evidence to optimize hematology trial outcomes, ensuring faster, more effective drug development.
Our experts help you stay at the forefront of the industry — and ahead of change.

Clinical Trialblazers
Step into the world of biotech leaders and hear the untold stories behind their journeys to bring breakthrough innovations to life.
Honest conversations with the experts shaping what's next
Thinking about joining a clinical trial? Learn the drug development process, what it’s like to participate, how to find a trial, and answers to frequently asked questions.
Clinical trials provide patients with access to innovative investigational treatments that advance medical research. Participation requires careful consideration that weighs both the benefits and risks.

Patient Stories
Clinical study participation represents a deeply personal decision with potentially far-reaching impact, as evidenced by these inspiring individual stories that highlight both the life-changing potential for participants and the broader advancement of healthcare for all.
We are one of the largest CROs in the world, speeding life-changing medicine to market by engaging patients With Heart™. Learn about who we are, what we do, and what we believe.
With decades of biopharmaceutical leadership experience and a deep dedication to patients, our executive team drives us forward in delivering better trials, faster.
Find key information on our policies, strategies, pay data, and more.
Explore end-to-end solutions throughout development — from portfolio optimization and regulatory strategy, to Phase I-IV clinical trials, market access planning, and more.
Our team optimizes your portfolio utilizing integrated expert clinical, regulatory, and market access strategies, enabling earlier and more informed risk-reward decisions.
Our multi-disciplinary early phase approach accelerates the path to proof of concept by integrating diverse expertise to optimize study design, generate robust clinical evidence, and reduce gaps between development phases.
We deliver whole-study solutions with integrated strategies that ensure safety, data integrity, and regulatory compliance. We design patient-informed protocols that remove participation barriers, accelerate enrollment, and increase the likelihood of successful drug launches.
Our team of former regulators and HTA professionals provide tailored regulatory, compliance, and market access strategies across specialized therapeutic areas, creating customized pathways to maximize global market reach throughout your product's lifecycle.
We enhance your product's value story through post-approval studies and holistic lifecycle management services that satisfy regulators and payers while building stakeholder trust and maximizing your drug's market impact throughout its entire lifecycle.
ParexelAI leverages our full suite of AI capabilities to deliver with greater speed, quality, and efficiency.

ParexelAI
ParexelAI is a proprietary AI-enabled clinical development suite that accelerates patient outcomes by combining Parexel's operational expertise with cutting-edge AI technology.
Utilize our expertise across therapeutic areas, combining innovative trial designs, leading clinical and regulatory expertise, global reach, and a passion for changing patient lives.
Our team delivers high-quality clinical trials through forward-thinking medical expertise across multiple indications by combining strategic insight with operational excellence to support programs of all sizes.
Our infectious disease and vaccines cro services help treat and prevent life-threatening illnesses. Learn how our team of experts can aid in any complex trial.
Discover our inflammation and immunology CRO services. We bring agile support and a unique MOA-driven model to inflammation and immunology.
Parexel is a leading Oncology CRO with more than 80 ex-agency regulators and nearly 2,500 sites globally. Learn more about our oncology indications.
As a leading neuroscience CRO, we leverage global site relationships, specialized resources, and indication-specific expertise to accelerate breakthroughs in neurological and psychiatric treatments for patients worldwide.
As a top hematology CRO, our integrated teams use advanced analytics and real-world evidence to optimize hematology trial outcomes, ensuring faster, more effective drug development.
Our experts help you stay at the forefront of the industry — and ahead of change.

Clinical Trialblazers
Step into the world of biotech leaders and hear the untold stories behind their journeys to bring breakthrough innovations to life.
Honest conversations with the experts shaping what's next
Thinking about joining a clinical trial? Learn the drug development process, what it’s like to participate, how to find a trial, and answers to frequently asked questions.
Clinical trials provide patients with access to innovative investigational treatments that advance medical research. Participation requires careful consideration that weighs both the benefits and risks.

Patient Stories
Clinical study participation represents a deeply personal decision with potentially far-reaching impact, as evidenced by these inspiring individual stories that highlight both the life-changing potential for participants and the broader advancement of healthcare for all.
We are one of the largest CROs in the world, speeding life-changing medicine to market by engaging patients With Heart™. Learn about who we are, what we do, and what we believe.
With decades of biopharmaceutical leadership experience and a deep dedication to patients, our executive team drives us forward in delivering better trials, faster.
Find key information on our policies, strategies, pay data, and more.
BIO
Senior Vice President, and Global Head of Advanced Analytics, RWE & HEOR
Jackie is a senior leader within Access Consulting at Parexel, responsible for the Health Economics strategy, modelling and Advanced Analytics teams. Jackie has extensive experience in conducting research across a range of therapeutic areas to deliver evidence on the differentiated value of the asset.
In her role at Parexel, Jackie is responsible for strategic leadership and technical expertise. This includes the development of AI-enabled solutions to enhance data generation and evidence analysis, to drive better decision-making for improved patient outcomes.
Work Experience
Jackie is an economist with over 20 years of progressive experience in the application of econometric principles and statistical data analysis to real-world issues. Prior to joining Parexel, she worked as a senior manager in Global Health Economics at Amgen where she was a member of the HTA Taskforce. This taskforce was charged with reviewing and critiquing the scoping documents developed by the Institute of Clinical and Economic Review as well as the meta-analyses and modelling techniques included in the research plans and evidence reports. Jackie also worked as a director of research operations and senior economist at Precision Health Economics where she was responsible for developing proposals and executing projects on several oncology and immune oncology assets to support regulatory approval, value messaging, and market access in various regions. In addition, Jackie has held research and consulting roles at Endurance Reinsurance, Analysis Group, and the Public Economics and Macroeconomics Divisions of the World Bank in Washington DC.
Education
Jackie completed her PhD at Cornell University following a pre-doctoral in economics at Yale University.
Whitepaper
Employing Bayesian survival and cost-effectiveness modelling for more informed healthcare decision-making: Practical overview and current perspectives
Blog
Transforming evidence generation: How predictive AI can optimize clinical development
Blog
Using ethical AI to streamline HEOR
Article
How biotechs can strengthen their value story with advanced analytics
Whitepaper
Employing Bayesian survival and cost-effectiveness modelling for more informed healthcare decision-making: Practical overview and current perspectives
Blog
Transforming evidence generation: How predictive AI can optimize clinical development
Blog
Using ethical AI to streamline HEOR
Article
How biotechs can strengthen their value story with advanced analytics
Learn More